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break-word'>

<div class=WordSection1>

<p class=MsoNormal><a name="_MailOriginal"><o:p>&nbsp;</o:p></a></p>

<p class=MsoNormal><span style='mso-bookmark:_MailOriginal'><span
style='color:white'>TRACK: Newsletter - Issue 03 - 11 May 2021<o:p></o:p></span></span></p>

<p class=MsoNormal><span style='mso-bookmark:_MailOriginal'><o:p>&nbsp;</o:p></span></p>

<div align=center>

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              <p class=MsoNormal align=center style='text-align:center;
              line-height:150%'><span style='mso-bookmark:_MailOriginal'><span
              style='font-size:12.0pt;line-height:150%;font-family:"Helvetica",sans-serif;
              color:#757575'>Issue 3&nbsp; &nbsp;|&nbsp; 11&nbsp;May 2021&nbsp;<o:p></o:p></span></span></p>
              </td>
              <span style='mso-bookmark:_MailOriginal'></span>
             </tr>
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            <span style='mso-bookmark:_MailOriginal'></span>
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            -ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'>
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              -webkit-text-size-adjust: 100%'>
              <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0
               width="100%" style='width:100.0%;background:#55B3D8;border-collapse:
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               min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'>
               <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:
                yes'>
                <td valign=top style='padding:13.5pt 13.5pt 13.5pt 13.5pt'>
                <p class=MsoNormal align=center style='text-align:center;
                line-height:150%'><span style='mso-bookmark:_MailOriginal'><strong><span
                style='font-size:13.5pt;line-height:150%;font-family:"Helvetica",sans-serif;
                color:#F2F2F2'>Study Overview </span></strong></span><span
                style='mso-bookmark:_MailOriginal'><span style='font-size:10.5pt;
                line-height:150%;font-family:"Helvetica",sans-serif;color:#F2F2F2'><br>
                </span></span><span style='mso-bookmark:_MailOriginal'><span
                style='font-size:12.0pt;line-height:150%;font-family:"Helvetica",sans-serif;
                color:#F2F2F2'>The TRACK trial will evaluate whether a small
                dose of rivaroxaban, a blood-thinning medication, would reduce
                cardiovascular death or major cardiovascular events in patients
                with advanced stages of chronic kidney disease.</span></span><span
                style='mso-bookmark:_MailOriginal'><span style='font-size:10.5pt;
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                <o:p></o:p></span></span></p>
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          </div>
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         <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:
          yes'>
          <td valign=top style='padding:6.75pt 13.5pt 6.75pt 13.5pt;-ms-text-size-adjust: 100%;
          -webkit-text-size-adjust: 100%'>
          <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0
           align=right width="100%" style='width:100.0%;background:white;
           border-collapse:collapse;mso-yfti-tbllook:1184;mso-table-lspace:
           2.25pt;mso-table-rspace:2.25pt;mso-table-anchor-vertical:paragraph;
           mso-table-anchor-horizontal:column;mso-table-left:right;mso-table-top:
           middle;mso-padding-alt:0cm 0cm 0cm 0cm;-ms-text-size-adjust: 100%;
           -webkit-text-size-adjust: 100%'>
           <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'>
            <td width=546 valign=top style='width:409.5pt;padding:13.5pt 13.5pt 0cm 13.5pt;
            -ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'>
            <p class=MsoNormal align=center style='text-align:center;
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            style='font-size:13.0pt;line-height:150%;font-family:"Arial",sans-serif;
            color:#0099FF'>Participant Recruitment</span></strong></span><span
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            line-height:150%;font-family:"Helvetica",sans-serif;color:#222222'><o:p></o:p></span></span></p>
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           </tr>
           <tr style='mso-yfti-irow:1;mso-yfti-lastrow:yes'>
            <td valign=top style='padding:6.75pt 0cm 0cm 0cm;-ms-text-size-adjust: 100%;
            -webkit-text-size-adjust: 100%'>
            <p class=MsoNormal><span style='mso-bookmark:_MailOriginal'><span
            style='color:black;mso-color-alt:windowtext'><span
            style='mso-no-proof:yes'><img width=560 height=343 id="_x0000_i1029"
            src="https://mcusercontent.com/16135105b84da36a23e269059/images/46400521-404b-de04-4bf8-31b1ad80ace9.png"></span></span><o:p></o:p></span></p>
            </td>
            <span style='mso-bookmark:_MailOriginal'></span>
           </tr>
          </table>
          <span style='mso-bookmark:_MailOriginal'></span></td>
          <span style='mso-bookmark:_MailOriginal'></span>
         </tr>
        </table>
        <p class=MsoNormal><span style='mso-bookmark:_MailOriginal'><o:p>&nbsp;</o:p></span></p>
        <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0
         width="100%" style='width:100.0%;border-collapse:collapse;mso-yfti-tbllook:
         1184;mso-padding-alt:0cm 0cm 0cm 0cm;-ms-text-size-adjust: 100%;
         -webkit-text-size-adjust: 100%'>
         <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:
          yes'>
          <td valign=top style='padding:6.75pt 13.5pt 6.75pt 13.5pt;-ms-text-size-adjust: 100%;
          -webkit-text-size-adjust: 100%'>
          <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0
           align=right width="100%" style='width:100.0%;border-collapse:collapse;
           mso-yfti-tbllook:1184;mso-table-lspace:2.25pt;mso-table-rspace:2.25pt;
           mso-table-anchor-vertical:paragraph;mso-table-anchor-horizontal:
           column;mso-table-left:right;mso-table-top:middle;mso-padding-alt:
           0cm 0cm 0cm 0cm;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'>
           <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'>
            <td width=546 valign=top style='width:409.5pt;padding:13.5pt 13.5pt 0cm 13.5pt;
            -ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'>
            <p class=MsoNormal align=center style='text-align:center;
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            style='font-size:12.0pt;line-height:150%;font-family:"Arial",sans-serif;
            color:#0099FF'>Meet the Team</span></strong></span><span
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            line-height:150%;font-family:"Helvetica",sans-serif;color:#222222'><o:p></o:p></span></span></p>
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            -webkit-text-size-adjust: 100%'>
            <p class=MsoNormal><span style='mso-bookmark:_MailOriginal'><span
            style='mso-no-proof:yes'><img width=564 height=467 id="_x0000_i1028"
            src="https://mcusercontent.com/16135105b84da36a23e269059/images/a78d8746-c3d3-4406-8ed9-93a2d9e072fa.png"></span><o:p></o:p></span></p>
            </td>
            <span style='mso-bookmark:_MailOriginal'></span>
           </tr>
          </table>
          <span style='mso-bookmark:_MailOriginal'></span></td>
          <span style='mso-bookmark:_MailOriginal'></span>
         </tr>
        </table>
        <p class=MsoNormal><span style='mso-bookmark:_MailOriginal'><o:p>&nbsp;</o:p></span></p>
        <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0
         width="100%" style='width:100.0%;border-collapse:collapse;mso-yfti-tbllook:
         1184;mso-padding-alt:0cm 0cm 0cm 0cm;-ms-text-size-adjust: 100%;
         -webkit-text-size-adjust: 100%'>
         <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:
          yes'>
          <td valign=top style='padding:6.75pt 13.5pt 6.75pt 13.5pt;-ms-text-size-adjust: 100%;
          -webkit-text-size-adjust: 100%'>
          <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0
           align=right width="100%" style='width:100.0%;border-collapse:collapse;
           mso-yfti-tbllook:1184;mso-table-lspace:2.25pt;mso-table-rspace:2.25pt;
           mso-table-anchor-vertical:paragraph;mso-table-anchor-horizontal:
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           0cm 0cm 0cm 0cm;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'>
           <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'>
            <td width=546 valign=top style='width:409.5pt;padding:13.5pt 13.5pt 0cm 13.5pt;
            -ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'>
            <p class=MsoNormal align=center style='text-align:center;
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            line-height:150%;font-family:"Helvetica",sans-serif;color:#222222'><o:p></o:p></span></span></p>
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            To remain up to date on site status, visit;&nbsp;</span></span><a
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            target="_blank"><span style='mso-bookmark:_MailOriginal'><span
            style='font-size:10.5pt;line-height:150%;font-family:"Helvetica",sans-serif;
            color:#007C89'>https://www.tracktrial.org/participating-sites/</span></span><span
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            line-height:150%;font-family:"Helvetica",sans-serif;color:#222222'><o:p></o:p></span></span></p>
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        <p class=MsoNormal><span style='mso-bookmark:_MailOriginal'><o:p>&nbsp;</o:p></span></p>
        <table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0
         width="100%" style='width:100.0%;border-collapse:collapse;mso-yfti-tbllook:
         1184;mso-padding-alt:0cm 0cm 0cm 0cm;min-width: 100%;-ms-text-size-adjust: 100%;
         -webkit-text-size-adjust: 100%'>
         <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:
          yes'>
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